2001 International Conference of the American Thoracic Society,
San Francisco, CA. May 2001.
Hirsch-Moverman Y, Gee V, Nader
N, Daud A, Colson PW, El-Sadr W. Treatment Preferences
Among Patients Screened For Latent Tb Infection At Harlem.
Treatment (tx) of Latent Tuberculosis Infection (LTBI) has
traditionally involved 6 - 12 mos of isoniazid (INH). Shorter
course regimens (RIF/PZA for 2 mos) have recently been offered
but involve more pills and side effects. Little is known about
patient (pt) preferences for these LTBI regimens.
We assessed pts demographics, TB knowledge, and treatment
preferences in Harlem. The preferences portion included 6
factors relating to treatment preferences, a presentation
of two treatment options for LTBI treatment, treatment preference
and reason for it.
Of 69 patients, 81% were African-American, 9% Latino, 30%
foreign-born, mean age of 38 years, 41% had a history of homelessness,
54% had completed high school, and 10% were previously treated
for LTBI. Fifty five percent of pts preferred the short-course
tx. Those who preferred the longer treatment tended to emphasize
the lack of side effects (55%) while those who preferred shorter-course
regimens mentioned length of tx (92%).
Different pts emphasize various factors in their treatment
preference of LTBI tx. Further research is needed on pt satisfaction
and tx completion of those regimens.